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Carlos Rodríguez Caso

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Carlos Rodríguez-Caso, PhD

Associate Professor (Profesor Titular de Universidad)

carlos.rodriguez (at) uma.es

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ABOUT ME:

With a biology background my research interest is about the principles of organisation behind complex (biological) systems. For that, my scientific career spams a multidisciplinar trajectory with contributions in the field of systems biology, synthetic biology and complexity. From a systems biology view I have worked in cancer, tissue homeostasis, evolution, genetics, metabolism and artificial life with contributions in the field of physics using complex networks theory for the study of complex systems. In the last years, from a synthetic biology approach, with an engineering perspective, I have combined both theory and experiments to study the principles of design of genetic circuits and cell computation.

SELECTED PUBLICATIONS:

Carbonell-Ballestero, M., García-Ramallo, E., Montañez, R., Rodríguez-Caso, C.*, & Macía, J.* (2016). Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law. Nucleic acids research44(1), 496-507. (link)

Carbonell-Ballestero, M., Duran-Nebreda, S., Montañez, R., Solé, R., Macía, J.,* & Rodríguez-Caso, C.* (2014). A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology. Nucleic acids research42(22), 14060-14069. (link)

Corominas-Murtra, B., Goñi, J., Solé, R. V.,* & Rodríguez-Caso, C.* (2013). On the origins of hierarchy in complex networks. Proceedings of the National Academy of Sciences110(33), 13316-13321. (link)

Conde-Pueyo, N., Munteanu, A., Solé, R. V., & Rodríguez-Caso, C*. (2009). Human synthetic lethal inference as potential anti-cancer target gene detection. BMC Systems Biology3(1), 1-15. (link)

Rodríguez-Caso, C., Montañez, R., Cascante, M., Sánchez-Jiménez, F., & Medina, M. A. (2006). Mathematical modeling of polyamine metabolism in mammals. Journal of Biological Chemistry281(31), 21799-21812. (link)

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